Cross-Coupling Reaction of Organoboron Compounds via Base-Assisted Transmetalation to Palladium(II) Complexes
نویسنده
چکیده
Until recently, organoboronic acids have been of limited use in organic synthesis due to their low reactivity for ionic reactions. During the past two decades; however, it has become increasingly clear that they are valuable reagents capable of undergoing many carbon-carbon bond formations in organic syntheses. In 1979, catalytic carbon-carbon bond formation, via transmetalation between organoboron compounds and palladium(II) halides, was found to proceed in the presence of a base. 1 Historical Perspectives Although organoboronic acids are highly advantageous as reagents in
منابع مشابه
New synthetic transformations via organoboron compounds
It was previously reported that the palladium-catalyzed cross-coupling reaction of 1-alkenylboron compounds with various vinylic or aryl halides in the presence of base provides the corresponding coupling products in high yields, stereoand regioselectively. The recent progress of such reactions, including the reaction of sterically hindered arylboronic acids with sterically hindered haloarenes,...
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